August 13, 2009
Tripe palms is a very rare skin disease which is characterised by thickened velvety palms that have the appearance of tripe – the stomach lining of beef, pork, or sheep. If tripe palms is featured with acanthosis nigricans (a brown to black, poorly defined, velvety hyperpigmentation of the skin), the cause is usually related to stomach- (35%) or lung cancer (11%).
Some statistics on ‘tripe palms’ & cancer:
“In over 40% of patients, tripe palms are the first sign of an undiagnosed cancer, hence all patients should undergo a full diagnostic workup for an associated malignancy, particularly lung cancer, gastrointestinal carcinoma, or a colonic polyps.”
“There is no specific treatment for tripe palms. It has been reported that approximately 30% of cases resolve once the underlying cancer is treated. However, tripe palms inconsistently respond to successful therapy and may persist for many years despite remission of the underlying cancer.”
Approximately in 90% of people having tripe palms this unusual hand characteristic can be associated with internal malignancy, for example a colonic polyps.
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