Most of us have fingerprints, but some people are born with missing fingerprints. Only four families around the world are known to have been born with this disorder – a disease called ‘adermatoglyphia’. Recently dermatologists have found adermatoglyphia in a Swiss family – 9 out of 16 members have no fingerprints – is caused by a smaller version of a gene called SMARCAD1!

Almost every person is born with fingerprints, and everyone’s are unique. In an effort to find the cause of the disease, dermatologist Eli Sprecher sequenced the DNA of 16 members of one family with adermatoglyphia in Switzerland. Seven had normal fingerprints, and the other nine did not. After investigating a number of genes to find evidence of mutation, the researchers came up empty-handed—until a grad student finally found the culprit, a smaller version of a gene called SMARCAD1

The larger SMARCAD1 is expressed throughout the body, but the smaller form acts only on the skin. Sure enough, the nine family members with no fingerprints had mutations in that gene.

Being born without fingerprints doesn’t occur simply because one gene has been turned on or off, Sprecher said. Rather, the mutation causes copies of the SMARCAD1 gene to be unstable.


Full story about missing fingerprints in a Swiss family:

Missing fingerprints in a Swiss family caused by SMARCAD1 gene!

Psoriasis is a common skin condition that causes skin redness and irritation. Most persons with psoriasis have thick, red skin with flaky, silver-white patches called scales. The diseases is seen in about 1% to 3% of the world population.

The hand in psoriasis shows many more stricking features that relate to the disease. Especially the fingernails display often typical characteristics, including e.g. nail pitting, onycholysis, oil drop signs & nail dystrophy – which are all featured in the video above presented by Dr. James L. Campbell Jr., MD.

But there are many other hand & nail characteristics involved in psoriasis. The following article present an overview of 24 hand markers in psoriasis:

HANDS & PSORIASIS: 24 hand markers


A classic example of the hand in psoriasis vulgaris:

The “Preacher Sign” involves the inability to flatten the hands against each other – a hand characteristic that is frequently seen in diabetes mellitus patients.

Diabetes mellitus belongs to a category of diseases that is known for having quite a few hand markers that ‘signal’ the development of the disease. Type 1 and type 2 have many common characteristics regarding the hands, but one has to be aware that some of them are limited to only one variant of the disease.

The most revealing dimensions of the hand in diabeter are: the MOTORICS (including the “Preacher Sign”), the FINGERNAILS, the SKIN QUALITY & the DERMATOGLYPHICS. And even the notorious simian crease is about twice to four times more often seen among diabetic patients – compared to the general population.
The following article presents an overview of 33 hand markers for Diabetes Mellitis – type 2 (all reported features have been confirms as ‘signficant’ in various scientific studies:
 
 
(A ‘phantom picture’ for the hand in diabetes will become available later)

Nail clubbing may signal lung, heart & stomach diseases.

Nail clubbing is found in 29% of lung cancer patients!

Nail clubbing has been known since the early days of the Greek philosopher Hippocrates, who recognized nail clubbing as a classic sign of disease. Today nail clubbing (a.k.a. ‘fingernail clubbing’ or the ‘Hippocratic fingernail’) is associated various lung diseases, especially lung cancer with non–small cell lung carcinoma. Nail clubbing is also linked with heart problems and gastrointestinal problems – but these are less common than lung problems.

Statistics on nail clubbing & lung cancer:

“Nail clubbing has been reported in 29% of patients with lung cancer and is observed more commonly in patients with non–small cell lung carcinoma (35%) than in patients with small cell lung carcinoma (4%).”

How to recognize ‘clubbing fingernails’?

Clubbing is usually a painless but complex fingernail disorder which often goes unnoticed of it’s presence in the hands of patients!

In individuals without clubbing, if two opposing fingers are placed together, a diamond-shaped window will appear. In clubbing, this window is obliterated and the distal angle formed by the two nails becomes wider. This is known as the Schamroth sign window test.

Schamroth's windows test is used in the diagnosis of nail clubbing.

SUGGESTION FOR FURTHER READING:

The clubbing nail: developments, treatment & prevention!
Hands on lung cancer: the clubbing fingernail!
Fingernail disorders & medical hand analysis!
What are the most common nail disorders?
Megan Fox has a ‘clubbed thumb’ – not to be confused with ‘fingernail clubbing’!

Despite swine flu many people haven't improved their hand washing habit!

Hands on hand hygiene: how good is your hand washing habit?

A new US survey has indicated that despite the swine flu, many people haven’t changed their washing hands habits. Did you try to improve your hand washing habit?

The survey was conducted online July 28-31 and involved 1,020 American adults across the country aged 18 to 65. Jon Dommisse, director of marketing and product development at Bradley Corporation (conductor of the survey) said:

“…they wash their hands no more or less frequently. We found the response to the H1N1 question extremely surprising, especially since the medical community has said over and over that hand washing is the best defense against the spread of cold and flu viruses.”

Overall, 87 percent of respondents said they did wash their hands after using public lavatories, but other responses indicated that some may have exaggerated how often they actually did the job correctly. When asked if they had also used soap, the numbers declined only slightly, to 86 percent; yet 55 percent of the group admitted on occasion they’ve simply rinsed, without using soap.

Just remember…

THE U.S. CENTERS FOR DISEASE CONTROL AND PREVENTION SAYS …

HAND WASHING IS CRITICAL IN PREVENTING ILLNESS!!!

Only a few days ago a few more swine flu facts were described by World Health Organisation Director General Margaret Chan in an interview:

“…This virus [H1N1 influenza A] travels at an unbelievable, almost unheard of speed. In six weeks it travels the same distance that other viruses take six months to cover. … Sixty percent of the deaths cover those who have underlying health problems. This means that 40 percent of the fatalities concern young adults – in good health – who die of a viral fever in five to seven days. This is the most worrying fact, up to 30 percent of people in densely populated countries risked getting infected …While 90 percent of severe and fatal cases occur in people aged above 65 in seasonal flu, most of those who die from swine flu are under the age of 50.”

MORE DETAILS AVAILABLE AT:

Hands on ‘hand hygiene’!
Swine flu prevention is a matter of ‘hand hygiene’!
Hand Hygiene: warm air dryers increase bacteria on hands!
More hand hygiene news!

Skin care: hand washing and applying hand cream takes 9 steps!