FRAGILE X SYNDROME – 28 Hand characteristics in the genetic syndrome variant of autism!

February 22, 2010

27 Characteristics of the hand in Fragile X syndrome (Xq27).

Phantom picture of the hand in Fragile X syndrome!

In 1986 A. Rodewald et al. presented the first ‘phantom picture’ describing the typical hand characteristics in Fragile X syndrome (e.g. hand calluses & flexible finger phalange joints). But more detailed ‘phantom pictures’ were never presented since then. This month (february 2010) a more detailed updated version of the visualisation became available – featuring 28 characteristics of the hand in Fragile’s syndrome!

What are the most common hand characteristics in Fragile X syndrome?

HAND LINES:
A common characteristic is the presence of the famous ‘simian line‘; an alternative is the presence of a Sydney line.

DERMATOGLYPHICS:
Here one should especially notice the fingerprints of the 3rd finger (and the 2nd + 4th finger); often these demonstrate the presence of ‘radial loop’ patterns and/or arch patterns (the normal ‘ulnar loop’ patterns are less common in Fragile X syndrome) – combined with a ‘transverse’ pattern in the palmar ridge lines in the distal palmar zone.

HAND SHAPE:
The palm width (hand breadth) is relatively broad, and the palm length is usually a bit short. Finger length is relatively long compared to the palm length, but slightly short compared to the palm breadth.

NOTICE: The author of the new ‘phantom picture’ for Fragilex syndrome described a specific guideline which states that in most cases of Fragile X syndrome certain combinations of the 28 characteristics are found in both the fingers AND the palm of the hand!

More details available at:
How to use the famous ‘simian crease’ as a marker in Fragile X syndrome!

Photo: example of a baby hand with hyperextensible finger joints – a common feature in Fragile X syndrome.
Example of a baby hand with hyperextensible finger joints - a common feature in Fragile X syndrome.

Advertisements

One Response to “FRAGILE X SYNDROME – 28 Hand characteristics in the genetic syndrome variant of autism!”


  1. I understand why she some feel that autism is a gift, but I doubt they felt that way growing up, and I doubt that all of the parents who have autistic children at the other of the spectrum feel that way. It’s a gift only when one makes it into one. A good lesson that to learn is not to be so hasty to give up on a child at such a young age. It seems like doctors categorize autistic children very young, and that sets the tone for the rest of their lives. As far as we’ve come, there is still much that medical science does not understand and cannot explain about autistic children, or many other things for that matter.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s